A Pathogenic Mechanism in Huntington's Disease Involves Small CAG-Repeated RNAs with Neurotoxic Activity | PLOS Genetics
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Therapeutic approaches for the treatment of HD and other CAG repeat... | Download Scientific Diagram
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A CAG repeat-targeting artificial miRNA lowers the mutant huntingtin level in the YAC128 model of Huntington's disease: Molecular Therapy - Nucleic Acids
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Molecular genesis of Huntington's disease, illustration. Expansion of the CAG trinucleotide sequence in the htt gene causes production of mutated Huntingtin protein leading to neurodegeneration, atrophy of brain basal ganglia, involuntary movements
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Frontiers | Protein Aggregation Inhibitors as Disease-Modifying Therapies for Polyglutamine Diseases
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In silico designing of putative peptides for targeting pathological protein Htt in Huntington's disease - ScienceDirect
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Molecular Genesis Huntington's Disease Illustration Expansion Cag Trinucleotide Sequence Htt Stock Photo by ©katerynakon 474065032
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Structure and putative protein binding properties of the CAG repeats... | Download Scientific Diagram
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Huntington's Disease Research: Shutting down the mutant gene – HudsonAlpha Institute for Biotechnology
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IJMS | Free Full-Text | Decreased Interactions between Calmodulin and a Mutant Huntingtin Model Might Reduce the Cytotoxic Level of Intracellular Ca2+: A Molecular Dynamics Study
The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain | PLOS ONE
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Discovery of a potent small molecule inhibiting Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein | Scientific Reports
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